Apoptosis Activator 2 ( —— )

产品货号. M15971 CAS No. 79183-19-0

COA

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HPLC

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产品名称

Apoptosis Activator 2
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

An apoptosis activator that strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation.
产品描述

An apoptosis activator that strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation; leads to the destruction of cells (Apaf-1 dependent) with IC50 of 4 uM; exert cytostatic and cytotoxic effects on a variety of cancer cell lines while having little or no activity against the normal cell lines tested.
同义词

——
通路

Apoptosis
靶点

Apoptosis
受体

Caspase-3
研究领域

Cancer
适应症

——

1. Nguyen JT, et al. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7533-8.
2. Farivar TN, et al. N Am J Med Sci. 2012 Nov;4(11):582-5.

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